Screen services are indispensable in modern drug discovery, facilitating the identification of potential drug candidates from vast compound libraries. These services utilize various screening techniques to evaluate compound interactions with biological targets, ultimately expediting the drug development process. At Alfa Chemistry, we offer a comprehensive range of screen services tailored to meet the diverse needs of our clients, including:
DNA-Encoded Libraries (DELs) Screening
This approach enables rapid identification of hits with high affinity and specificity, significantly accelerating lead discovery efforts.
High-Throughput Screening (HTS)
By automating the screening process, HTS allows for the evaluation of thousands to millions of compounds in a short period, providing valuable insights into compound activity and potential drug candidates.
Target-based screening involves screening compound libraries against specific biological targets, such as enzymes, receptors, or proteins involved in disease pathways.
By assessing the overall biological response to compounds, phenotypic screening can uncover novel mechanisms of action and identify compounds with therapeutic potential across a range of diseases.
Virtual screening utilizes computational methods to screen compound libraries in silico, based on their predicted interactions with biological targets.
Fragment-Based Screening (FBS)
Fragment-based screening (FBS) involves screening libraries of small, low molecular weight compounds, known as fragments, against biological targets.
Biochemical Selection Services
Alfa Chemistry has the ability to provide biochemical selection services with one-bead-one-compound DNA-encoded chemical libraries against soluble targets.
Whether it's designing custom libraries, developing novel assays, or implementing specialized screening protocols, custom screening services provide tailored solutions to drive drug discovery efforts forward.
Screen services play a vital role in accelerating drug discovery efforts, providing researchers with the tools and technologies needed to identify potential drug candidates efficiently. At Alfa Chemistry, our comprehensive range of screen services, coupled with our expertise and commitment to innovation, enables us to support and advance drug discovery projects across various therapeutic areas. Contact us today to learn more about our services and discover how we can empower your journey towards innovation and success.