VT103

• CAS: 2290608-13-6
• Catalog Number: ACM-MG-2290608136
• Category: Molecular Glues
• Molecular Weight: 410.42
• Molecular Formula: C18H17F3N4O2S
• Description: VT103 inhibits YAP/TAZ-TEAD promoted gene transcription, blocks TEAD auto-palmitoylation, and disrupts the interaction between YAP/TAZ and TEAD via inhibition of TEAD1 (IC50 = 1 nM).
• Synonyms: N-Methyl-3-(1-methylimidazol-4-yl)-4-[4-(trifluoromethyl)anilino]benzenesulfonamide
• IUPAC Name: N-methyl-3-(1-methylimidazol-4-yl)-4-[4-(trifluoromethyl)anilino]benzenesulfonamide
• SMILES: CNS(=O)(=O)C1=CC(=C(C=C1)NC2=CC=C(C=C2)C(F)(F)F)C3=CN(C=N3)C
• InChI: InChI=1S/C18H17F3N4O2S/c1-22-28(26,27)14-7-8-16(15(9-14)17-10-25(2)11-23-17)24-13-5-3-12(4-6-13)18(19,20)21/h3-11,22,24H,1-2H3
• InChI Key: LLCVDQHLYHBAHR-UHFFFAOYSA-N
• Solubility: Soluble in DMSO (at least 40 mg/ml)
• Appearance: Off-white solid
• Shipping: Room temperature
• Stability: Stable for up to 2 years when stored as supplied at room temperature. Solutions in DMSO may be stored at -20 °C for up to 3 months.
• Storage Conditions: Store at -20 °C