DS02312223

• CAS: 2253733-45-6
• Catalog Number: ACM-MG-2253733456
• Category: Molecular Glues
• Molecular Weight: 581.66
• Molecular Formula: C29H32FN5O5S
• Description: DS02312223 is a molecular glue that promotes the binding of RAS to PI3Kα, thereby enhancing glucose uptake in the absence of insulin.
• Synonyms: A1AZD
• IUPAC Name: tert-butyl N-[2-[2-[2-[4-[4-(2-amino-2-oxoethyl)-2-fluoroanilino]thieno[2,3-d]pyridazin-7-yl]phenoxy]ethoxy]ethyl]carbamate
• SMILES: CC(C)(OC(NCCOCCOC1=C(C=CC=C1)C2=C3SC=CC3=C(N=N2)NC4=C(C=C(C=C4)CC(N)=O)F)=O)C
• InChI: InChI=1S/C29H32FN5O5S/c1-29(2,3)40-28(37)32-11-12-38-13-14-39-23-7-5-4-6-19(23)25-26-20(10-15-41-26)27(35-34-25)33-22-9-8-18(16-21(22)30)17-24(31)36/h4-10,15-16H,11-14,17H2,1-3H3,(H2,31,36)(H,32,37)(H,33,35)
• InChI Key: NFCHONNVHGPRMI-UHFFFAOYSA-N
• Appearance: White to off-white solid
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Store at -20 °C