LXH-3-71

• CAS: 2251753-65-6
• Catalog Number: ACM-MG-2251753656
• Category: Molecular Glues
• Molecular Weight: 657.92
• Molecular Formula: C41H59N3O4
• Description: LXH-3-71 is a potent molecular glue PHGDH degrader. LXH-3-71 forms a dynamic chimera between PHGDH and the DDB1-CRL E3 ligase.
• Synonyms: EX-A10057
• IUPAC Name: (4aS,6aR,6aS,6bR,8aR,12aR,14bS)-N-[2-[(4-methoxyphenyl)carbamoylamino]ethyl]-2,2,6a,6b,9,9,12a-heptamethyl-11-methylidene-10-oxo-1,3,4,5,6,6a,7,8,8a,12,13,14b-dodecahydropicene-4a-carboxamide
• SMILES: C=C1C[C@]2([C@@](C(C)(C)C1=O)([H])CC[C@]3(C)[C@]2([H])CC=C4[C@]5([H])CC(C)(CC[C@@]5(CC[C@]43C)C(NCCNC(NC6=CC=C(C=C6)OC)=O)=O)C)C
• InChI: InChI=1S/C41H59N3O4/c1-26-24-38(6)31(37(4,5)33(26)45)16-17-40(8)32(38)15-14-29-30-25-36(2,3)18-20-41(30,21-19-39(29,40)7)34(46)42-22-23-43-35(47)44-27-10-12-28(48-9)13-11-27/h10-14,30-32H,1,15-25H2,2-9H3,(H,42,46)(H2,43,44,47)/t30-,31-,32+,38-,39+,40+,41-/m0/s1
• InChI Key: KHAFPBAKIVPZNQ-RRBGEOAMSA-N
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.