Structure

SR-4835

CAS
2387704-62-1
Catalog Number
ACM-MG-2387704621
Category
Molecular Glues
Molecular Weight
499.36
Molecular Formula
C21H20Cl2N10O

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Specification

Description
SR-4835 is a potent and selective inhibitor of cyclin-dependent kinases 12 and 13.
Synonyms
N-[(5,6-Dichloro-1H-benzimidazol-2-yl)methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-ylpurin-6-amine
IUPAC Name
N-[(5,6-dichloro-1H-benzimidazol-2-yl)methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-ylpurin-6-amine
SMILES
CN1C=C(C=N1)N2C=NC3=C(N=C(N=C32)N4CCOCC4)NCC5=NC6=CC(=C(C=C6N5)Cl)Cl
InChI
InChI=1S/C21H20Cl2N10O/c1-31-10-12(8-26-31)33-11-25-18-19(29-21(30-20(18)33)32-2-4-34-5-3-32)24-9-17-27-15-6-13(22)14(23)7-16(15)28-17/h6-8,10-11H,2-5,9H2,1H3,(H,27,28)(H,24,29,30)
InChI Key
FSELUFUYNUNZKD-UHFFFAOYSA-N
Solubility
Soluble in DMSO (>25 mg/ml)
Appearance
Off-white solid
Shipping
Room temperature
Stability
Stable for up to 2 years when stored as supplied at -20 °C. Solutions in DMSO may be stored at -20 °C for up to 3 months.
Storage Conditions
Store at -20 °C

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