3101-60-8 Purity
96%
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Specification
This paper reports initial testing results for a novel electrospun fiber mat utilizing polyisobutylene (PIB) as its unique macromolecular base. Self-supporting mats (203.75 and 295.5 g/m²) were electrospun from a PIB compound containing zinc oxide (ZnO). Results indicate the hydrophobic mats are non-cytotoxic, resist fibroblast adhesion and biofilm formation, and offer comfort and breathability suitable for masks. These properties highlight the mats' significant potential for personal protective equipment and other applications.
Performance of PIB-Based Fiber Mat
· Cytotoxicity: Statistical analysis showed that 24-hour exposure of cells to the mat release medium did not affect cell viability versus the control. However, 72-hour exposure reduced viable cells by approximately 25%. This indicates the ZnO-containing mats do not inhibit fibroblast growth but reduce their proliferation rate.
· Cell Adhesion: Two-photon microscopy revealed characteristic fibroblast staining (Vybrant DiD, red) was absent after both 24 h and 72 h incubations, suggesting no cell adhesion. The polymer and/or ZnO particles exhibited moderate green autofluorescence.
· Biofilm Formation: P. aeruginosa biofilm formation requires glucose, typically yielding optical density (OD595nm) values of 0.2-0.4 (up to 0.5 with added salt); inhibition reduces OD below 0.1. Figure 8 data demonstrate the tested mats effectively mitigated P. aeruginosa's biofilm-forming capacity.
Silicone resins are hyperbranched, near-spherical macromolecules of nanometer size, featuring numerous terminal organic groups. This structure allows them to function as functionalized silica nanoparticles miscible within polymer matrices. This paper examines mixtures of linear polyisobutylene (PIB) with methyl-terminated (MT) silicone resin.
Key Findings
Linear PIB and silicone resin exhibit partial mutual solubility, quantitatively dependent on the resin's molecular weight and terminal group type. At low resin concentrations, homogeneous mixtures form molecular nanocomposites: a continuous PIB matrix with dispersed nanoscale resin particles (siloxane core, organic shell). Achieving such nanocomposites at higher nanoparticle concentrations requires chemical similarity between the polymer matrix and the hyperbranched molecules' terminal groups. For PIB, longer terminal hydrocarbon groups are necessary; methyl groups are insufficient for homogeneity across any significant concentration range.
Increasing temperature improves component solubility (the mixtures exhibit an Upper Critical Solution Temperature, UCST), but solubility remains limited. Heterogeneous mixtures form emulsions, which under shear and high disperse phase content, can develop co-continuous or cylindrical morphologies. Blend viscosity shows a negative deviation from logarithmic additivity due to interlayer slip. PIB viscosity reduction stems from both dissolving low-viscosity resin and interfacial slip. Consequently, no single classical empirical equation describes the blend's viscosity concentration dependence. This requires a combined equation accounting for the transition from mutual dissolution dominance to interlayer slip dominance as concentration changes.