GSPT1 degrader-9

• CAS: 3034310-17-0
• Catalog Number: ACM-MG-3034310170
• Category: Molecular Glues
• Molecular Weight: 694.18
• Molecular Formula: C37H36ClN7O5
• Description: GSPT1 degrader-9 is a cereblon-based molecular glue degrader for G1 to S phase transition protein 1 (GSPT1) that degrades GSPT1 with a rate of 95% (1 μM) GSPT1 and 86% (0.1 μM).
• Synonyms: EX-A13216
• IUPAC Name: 5-[3-[2-[3-[3-(4-chloro-3-ethyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]-2-oxo-1,3-diazinan-1-yl]ethyl]azetidin-1-yl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
• SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CC(CCN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C4)C=C3C2=O)=O)=O
• InChI: InChI=1S/C37H36ClN7O5/c1-2-22-17-39-33-31(22)32(38)28(18-40-33)23-5-3-6-25(15-23)44-13-4-12-42(37(44)50)14-11-21-19-43(20-21)24-7-8-26-27(16-24)36(49)45(35(26)48)29-9-10-30(46)41-34(29)47/h3,5-8,15-18,21,29H,2,4,9-14,19-20H2,1H3,(H,39,40)(H,41,46,47)
• InChI Key: JIWPWTFFRDWHRI-UHFFFAOYSA-N
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.