BMS-986470

• CAS: 3036554-12-5
• Catalog Number: ACM-MG-3036554125
• Category: Molecular Glues
• Molecular Weight: 523.54
• Molecular Formula: C29H25N5O5
• Description: BMS-986470, a HbF-activating CRBN E3 ligase modulator (CELMoD), is an orally active dual molecular glue degrader targeting ZBTB7A and WIZ.
• Synonyms: GTPL14200
• IUPAC Name: 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-[[1-methyl-6-(2-methyl-4-pyridinyl)-2-oxo-3,4-dihydroquinolin-7-yl]amino]isoindole-1,3-dione
• SMILES: CC1=NC=CC(C2=CC3=C(N(C(CC3)=O)C)C=C2NC4=CC=CC5=C4C(N(C5=O)[C@H]6CCC(NC6=O)=O)=O)=C1
• InChI: InChI=1S/C29H25N5O5/c1-15-12-16(10-11-30-15)19-13-17-6-9-25(36)33(2)23(17)14-21(19)31-20-5-3-4-18-26(20)29(39)34(28(18)38)22-7-8-24(35)32-27(22)37/h3-5,10-14,22,31H,6-9H2,1-2H3,(H,32,35,37)/t22-/m0/s1
• InChI Key: WTHBTFQJBVJOAO-QFIPXVFZSA-N
• Appearance: Light yellow to yellow solid
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Store at -20 °C