BMS-986463

• CAS: 3025467-07-3
• Catalog Number: ACM-MG-3025467073
• Category: Molecular Glues
• Molecular Weight: 572.63
• Molecular Formula: C32H33FN4O5
• Description: BMS-986463, a CRBN E3 ligase modulator (CELMoD), is a WEE1 kinase molecular glue degrader.
• Synonyms: GTPL14190
• IUPAC Name: (3S)-3-[6-[(3S)-1-[[8-fluoro-2-(oxan-4-yl)quinolin-6-yl]methyl]pyrrolidin-3-yl]oxy-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
• SMILES: O=C1CC[C@@H](C(N1)=O)N2CC3=CC(O[C@H]4CCN(C4)CC5=CC(F)=C6N=C(C=CC6=C5)C7CCOCC7)=CC=C3C2=O
• InChI: InChI=1S/C32H33FN4O5/c33-26-14-19(13-21-1-4-27(34-30(21)26)20-8-11-41-12-9-20)16-36-10-7-24(18-36)42-23-2-3-25-22(15-23)17-37(32(25)40)28-5-6-29(38)35-31(28)39/h1-4,13-15,20,24,28H,5-12,16-18H2,(H,35,38,39)/t24-,28-/m0/s1
• InChI Key: JPTNRZBZSUZXCS-CUBQBAPOSA-N
• Appearance: White to off-white solid
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Store at -20 °C