IKZF2-degrader 2

• CAS: 2983841-00-3
• Catalog Number: ACM-MG-2983841003
• Category: Molecular Glues
• Molecular Weight: 509.96
• Molecular Formula: C26H25ClFN5O3
• Description: IKZF2-degrader 2 is a selective and orally active IKZF2 molecular glue degrader with DC50 values of 0.5 nM and 1.8 nM in HiBit and FACS.
• Synonyms: EX-A15980
• IUPAC Name: 3-[6-[5-chloro-1-methyl-4-(pyrrolidin-1-ylmethyl)pyrrolo[2,3-b]pyridin-6-yl]-7-fluoro-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
• SMILES: O=C1C2=C(CN1C3C(NC(CC3)=O)=O)C(F)=C(C4=C(Cl)C(CN5CCCC5)=C(C=CN6C)C6=N4)C=C2
• InChI: InChI=1S/C26H25ClFN5O3/c1-31-11-8-14-17(12-32-9-2-3-10-32)21(27)23(30-24(14)31)16-5-4-15-18(22(16)28)13-33(26(15)36)19-6-7-20(34)29-25(19)35/h4-5,8,11,19H,2-3,6-7,9-10,12-13H2,1H3,(H,29,34,35)
• InChI Key: JRGGAIVXJQWLAP-UHFFFAOYSA-N
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.