TCO are a class of click chemistry reagents containing a reactive TCO group. As dienophiles, TCO can react with tetrazines by inverse electron-demand Diels-Alder (IEDDA) click reaction, which is the fastest bioorthogonal reaction found so far, and the reaction rate can reach 10000 under physiological conditions without catalysts. Due to the high reaction rate and good biocompatibility, IEDDA click reaction is widely used in labeling and bioconjugation. The structure of TCO group is shown in scheme 1. Alfa Chemistry is a leading global supplier of click chemistry reagents, with many experienced chemistry masters and PhDs. We strive to provide our customers with the highest quality TCO. If you do not find what you need, please contact us. We also offer product customization according to your detailed requirements.
Scheme 1. The structure of TCO group.
| Product Name |
CAS |
Application |
Inquiry |
| TCO-NHS ester |
1191901-33-3 |
IEDDA Click Reaction |
Inquiry |
| rel-((1R,8S,9r)-Bicyclo[6.1.0]non-4-en-9-yl)methanol |
1312010-01-7 |
|
Inquiry |
| s-TCO-PNP |
1312010-03-9 |
|
Inquiry |
| Mal-s-TCO |
1312010-04-0 |
|
Inquiry |
| 5-AVA-TCO |
1354323-66-2 |
|
Inquiry |
| N-(4E)-TCO-L-lysine |
1380349-88-1 |
|
Inquiry |
| N-(4E)-TCO-N'-Fmoc-L-lysine |
1380349-90-5 |
|
Inquiry |
| (E)-cyclooct-4-en-1-yl (4-nitrophenyl) carbonate TCO |
1380416-34-1 |
|
Inquiry |
| Lys(s-TCO)-OH |
1384180-60-2 |
|
Inquiry |
| 2,5-Dioxopyrrolidin-1-yl (1R,8S,9r,E)-bicyclo[6.1.0]non-4-ene-9-carboxylate |
1410900-63-8 |
|
Inquiry |
| (1R,8S,9r,E)-bicyclo[6.1.0]non-4-ene-9-carboxylic acid |
1412393-96-4 |
|
Inquiry |
| TCO-PNB ester |
1438415-89-4 |
IEDDA Click Reaction |
Inquiry |
| Fmoc-Lys(s-TCO)-OH |
1493802-87-1 |
|
Inquiry |
| N-(2E)-TCO-L-lysine |
1580501-94-5 |
IEDDA Click Reaction |
Inquiry |
| rTCO-PNP carbonate |
1580501-97-8 |
|
Inquiry |
| Fmoc-Lys(r-TCO)-OH |
1580501-99-0 |
|
Inquiry |
| TCO-PEG3-maleimide |
1609659-01-9 |
IEDDA Click Reaction |
Inquiry |
| TCO - amine, HCl salt |
1609659-02-0 |
IEDDA Click Reaction |
Inquiry |
| TCO-amine |
1609736-43-7 |
IEDDA Click Reaction |
Inquiry |
| (S,E)-cyclooct-2-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate TCO |
1610931-22-0 |
|
Inquiry |
