Terminal Alkyne Custom Synthesis

Terminal alkynes are a kind of substances with the formula RC₂H, which can react with azide-bearing compounds via copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click reactions to yield stable triazoles. These triazoles are widely used in various fields, such as medical field, analysis and detection field, biological field, and so on. Therefore, it is essential to develop terminal alkynes for different purposes to promote the application of CuAAC click reactions. Alfa Chemistry is an ideal partner for the custom synthesis of various terminal alkynes. We have the ability to lead the new application of click chemistry by providing customized terminal alkynes. If you want to know more about our products, please contact us.

Our Services

Alfa Chemistry provides our consumers with custom synthesis services of many types of terminal alkynes, which include but are not limited to the following.

Bis-propargyl-PEG
Propargyl-PEG-alcohol
Propargyl-PEG-maleimide
Propargyl-PEG-methyl ester
t-Boc-N-amido-PEG-propargyl
Amine reactive terminal alkyne
Propargyl-PEG-(CH₂)₃-methyl ester

Rhodamine
Tos-PEG-alkyne
Alkyne-PEG-iodide
Propargyl-PEG-bromide
Propargyl-PEG-sulfonic acid
t-Boc-aminooxy-PEG-propargyl
Carboxyl reactive terminal alkyne

Propargyl-PEG-Ms
Propargyl-PEG-methane
Propargyl-PEG-CH₂CO₂tBu
Propargyl-PEG-t-butyl ester
Alkyne-ethyl-PEG-t-butyl ester
Carbonyl reactive terminal alkyne
…

Synthesis Methods

Synthesis of terminal alkynes
through α,β-elimination

Synthesis of terminal alkynes
through carbene rearrangement

Synthesis of terminal alkynes
through dehydrohalogenation and
related reactions

Why Choose Us?

Alfa Chemistry is confident to provide you with the most professional custom synthesis services. Reasons for choosing us include, but are not limited to, the following.

• Our synthesis cycle is short and efficiency is high.
• Our pricing is very competitive compared to many other reagent suppliers.
• We guarantee the superior quality of our products by providing real analytical data.
• We have a professional team with extensive experience in terminal alkyne synthesis.
• We provide the highest level of technical support 24 hours a day, 7 days a week, and on holidays as well.

Our Service Process

Customer Enquiry

Preliminary Negotiation

Order Confirmation

Lab Synthesis

Packing Shipment