Tetrazines
Tetrazines are a class of click chemistry labeling reagents containing a reactive tetrazine group with four nitrogen atoms. In the biology and chemistry fields, they have attracted significant attention due to their high reactivity with TCO in an inverse electron-demand Diels-Alder (IEDDA) click reaction followed by a retro Diels-Alder reaction in order to eliminate nitrogen gas. The reaction rate of IEDDA click reaction between tetrazines and TCO can reach 10000 under physiological conditions without catalysts. Tetrazines are widely used in live cell labeling, molecular imaging and other bioconjugation. The structure of tetrazine group is shown in scheme 1. Alfa Chemistry is a leading global supplier of click chemistry reagents, with many experienced chemistry masters and PhDs. We strive to provide our customers with the highest quality tetrazines. If you do not find what you need, please contact us. We also offer product customization according to your detailed requirements.
Scheme 1. The structure of tetrazine group.
| Product Name | CAS | Application | Inquiry |
|---|---|---|---|
| Tetrazine amine | 1092689-33-2 | IEDDA Click Reaction | Inquiry |
| Tetrazine-Ph-NHCO-C3-NHS ester | 1244040-64-9 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine amine | 1345955-28-3 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine-acid | 1380500-88-8 | IEDDA Click Reaction | Inquiry |
| Tetrazine-acid | 1380500-92-4 | IEDDA Click Reaction | Inquiry |
| Tetrazine-Amine monohydrochloride | 1416711-59-5 | IEDDA Click Reaction | Inquiry |
| Bz-(Me)Tz-NHS | 1454558-58-7 | IEDDA Click Reaction | Inquiry |
| Tetrazine-NHS ester | 1616668-55-3 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine-NHS ester | 1644644-96-1 | IEDDA Click Reaction | Inquiry |
| Trisulfo-Cy3 methyltetrazine | 1676067-48-3 | IEDDA Click Reaction | Inquiry |
| Tetrazine-PEG5-NHS ester | 1682653-80-0 | IEDDA Click Reaction | Inquiry |
| Tetrazine-biotin | 1714123-51-9 | IEDDA Click Reaction | Inquiry |
| Me-Tet-PEG4-Maleimide | 1715913-76-0 | IEDDA Click Reaction | Inquiry |
| Sulfo-Cy5-tetrazine | 1801695-57-7 | IEDDA Click Reaction | Inquiry |
| Sulfo-Cy5-methyltetrazine | 1801924-46-8 | IEDDA Click Reaction | Inquiry |
| Sulfo-Cy3-Methyltetrazine | 1801924-47-9 | Inquiry | |
| Biotin-MeTz | 1802883-51-7 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine-PEG4-acid | 1802907-91-0 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine-PEG5-NHS ester | 1802907-92-1 | IEDDA Click Reaction | Inquiry |
| Methyltetrazine-PEG5-alkyne | 1802907-97-6 | IEDDA Click Reaction | Inquiry |
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