BCN
BCN are a class of click chemistry reagents containing a very reactive BCN group, which can react with azide-tagged molecules or biomolecules to form triazole compounds by strain-promoted azide-alkyne cycloaddition (SPAAC) click reaction. This reaction can occur in aqueous buffers or organic solvents depending on the properties of substrate molecules. In addition, BCN can also react with nitrones via strain-promoted alkyne-nitrone cycloaddition (SPANC) click reaction. Common BCN include endo-BCN-OH, endo-BCN-PNB, endo-BCN-PEG-acid, and so on, which have been widely used in clinical, signaling pathway, proteolytic targeting chimera, PEG targeting modification, etc. The structure of BCN group is shown in scheme 1. Alfa Chemistry is a leading global supplier of click chemistry reagents, with many experienced chemistry masters and PhDs. We strive to provide our customers with the highest quality BCN. If you do not find what you need, please contact us. We also offer product customization according to your detailed requirements.
Scheme 1. The structure of BCN group.
| Product Name | CAS | Application | Inquiry |
|---|---|---|---|
| BCN-OH | 1263166-90-0 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-O-PNB | 1263166-91-1 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG3-biotin | 1263166-92-2 | SPAAC & SPANC Click Reaction | Inquiry |
| BCN-amine | 1263166-93-3 | SPAAC & SPANC Click Reaction | Inquiry |
| rel-((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate | 1426827-79-3 | SPAAC & SPANC Click Reaction | Inquiry |
| BCN-SS-amine | 1435784-65-8 | SPAAC & SPANC Click Reaction | Inquiry |
| APN-BCN | 1644038-97-0 | SPAAC & SPANC Click Reaction | Inquiry |
| BCN-PEG4-NHS ester | 1702356-19-1 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG3-NH2 | 1841134-72-2 | SPAAC & SPANC Click Reaction | Inquiry |
| BCN-PEG4-acid | 1881221-47-1 | SPAAC & SPANC Click Reaction | Inquiry |
| BCOT-PEF3-OPFP | 2101206-48-6 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG3-NHS ester | 2101206-94-2 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG8-acid | 2126805-02-3 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG3-mal | 2141976-33-0 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG12-NHS ester | 2183440-26-6 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG12-acid | 2183440-27-7 | SPAAC & SPANC Click Reaction | Inquiry |
| endo-BCN-PEG2-C2-NHS ester | 2243565-12-8 | SPAAC & SPANC Click Reaction | Inquiry |
| Aminooxy-PEG2-BCN | 2253965-14-7 | SPAAC & SPANC Click Reaction | Inquiry |
| BCN-PEG3-VC-PFP ester | 2353409-45-5 | SPAAC & SPANC Click Reaction | Inquiry |
| Gly-PEG3-endo-BCN | 2354291-37-3 | SPAAC & SPANC Click Reaction | Inquiry |
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