CAS
3036606-92-2 Purity
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3036606-92-2 Purity
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Shopping basket
VAV1 degrader-3
CAS
3050683-38-7
Catalog Number
ACM-MG-3050683387
Category
Molecular Glues
Molecular Weight
392.83
Molecular Formula
C22H17ClN2O3
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Specification
Description
VAV1 degrader-3 is an orally active VAV1 molecular glue degrader (DC50: 7 nM). VAV1 degrader-3 reduces immune cell activation, immune cell proliferation and the production of various cytokines. VAV1 degrader-3 can be used for research of inflammatory or autoimmune disorder. VAV1 degrader-3 inhibits disease progression in experimntal autoimmune encephalomyelitis (EAE) mouse model, Collagen-induced arthritis (CIA) mouse model, etc.
SMILES
ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(N4C(C=CC=C4)=O)C=C3
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
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