VAV1 degrader-2

• CAS: 3050683-29-6
• Catalog Number: ACM-MG-3050683296
• Category: Molecular Glues
• Molecular Weight: 393.87
• Molecular Formula: C22H20ClN3O2
• Description: VAV1 degrader-2 (Example 176) is a molecular glue degrader based on targeting VAV 1 with a DC50 of 4.41 nM. VAV1 degrader-2 can be used in the study of inflammatory and autoimmune diseases.
• IUPAC Name: 3-[2-chloro-3-[4-[(1-methylpyrazol-3-yl)methyl]phenyl]phenyl]piperidine-2,6-dione
• SMILES: ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(CC4=NN(C)C=C4)C=C3
• InChI: InChI=1S/C22H20ClN3O2/c1-26-12-11-16(25-26)13-14-5-7-15(8-6-14)17-3-2-4-18(21(17)23)19-9-10-20(27)24-22(19)28/h2-8,11-12,19H,9-10,13H2,1H3,(H,24,27,28)
• InChI Key: APSGONYGWYCOOJ-UHFFFAOYSA-N
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.