CAS
3050683-38-7 Purity
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3050683-38-7 Purity
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CB039
CAS
3056259-55-0
Catalog Number
ACM-MG-3056259550
Category
Molecular Glues
Molecular Weight
481.52
Molecular Formula
C23H23N5O5S
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Specification
Description
CB039 is a selective a molecular glue degrader that targets RBM39 (RNA-binding protein 39). CB039 promotes the formation of a ternary complex between RBM39 and the E3 ubiquitin ligase CUL4-DCAF15, leading to proteasomal degradation of RBM39. CB039 is promising for research of cancers with RBM39 dependency, such as acute myeloid leukemia (AML) and ovarian cancer.
SMILES
CC1=C2C(NC=C2C#N)=C(C=C1)NS(C3=CC=CC(NC(C(N4[C@H](CCC4)CO)=O)=O)=C3)(=O)=O
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
Please kindly note that our products are for research use only.
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