Structure

S234984

Catalog Number
ACM-MG-00084
Category
Molecular Glues
Molecular Weight
443.54
Molecular Formula
C26H29N5O2

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Specification

Description
S234984 is a molecular glue degrader. S234984 forms a stable ternary complex with wild-type KBTBD4 E3 ligase and HDAC2 to drive neomorphic ubiquitination and degradation of CoREST1 and LSD1.
SMILES
O=C(OC)C1=CC2=C(C(C(NCCCN3CCCC3)=NC(CC4=CC=CC=C4)=N5)=C5N2)C=C1
Appearance
White to off-white solid
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
Store at -20 °C

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Alfa Chemistry

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