Structure

NK7-902 diTFA

Catalog Number
ACM-MG-00082
Category
Molecular Glues
Molecular Weight
638.51
Molecular Formula
C26H28F6N4O8

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Specification

Description
NK7-902 diTFA is a selective and orally active CRBN-dependent NEK7 molecular glue degrader with Kd values of 1.5 and 2.6 μM for hNEK7 and mNEK7.
SMILES
CCN[C@@H]1CC[C@@H]2N(C3=CC=C(C(N(C4CCC(NC4=O)=O)C5=O)=O)C5=C3)[C@H]1CC2.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Appearance
Light yellow to yellow soild
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
Store at -20 °C

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Alfa Chemistry

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