ABS-752

• CAS: 2761170-84-5
• Catalog Number: ACM-MG-2761170845
• Category: Molecular Glues
• Molecular Weight: 291.28
• Molecular Formula: C14H14FN3O3
• Description: ABS-752 is a potent and orally active GSPT1 and NEK7 molecular glue degrader. ABS-752 shows cytotoxicity. ABS-752 decreases the protein expression of GSPT1 and SALL4, NEK7.
• Synonyms: 3-(5-(Aminomethyl)-6-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• IUPAC Name: 3-[6-(aminomethyl)-5-fluoro-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
• SMILES: O=C(C(N(CC1=C2C=C(F)C(CN)=C1)C2=O)CC3)NC3=O
• InChI: InChI=1S/C14H14FN3O3/c15-10-4-9-8(3-7(10)5-16)6-18(14(9)21)11-1-2-12(19)17-13(11)20/h3-4,11H,1-2,5-6,16H2,(H,17,19,20)
• InChI Key: VHUZYSKPEQGBJP-UHFFFAOYSA-N
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: Please store the product under the recommended conditions.