NP3-253

• CAS: 2557349-50-3
• Catalog Number: ACM-MG-2557349503
• Category: Molecular Glues
• Molecular Weight: 380.41
• Molecular Formula: C19H23F3N4O
• Description: NP3-253 functions as a molecular glue that prevents NACHT-subdomain rearrangements, locking NLRP3 in an inactive conformation.
• Synonyms: (R)-2-(6-((1-Ethylpiperidin-3-yl)amino)pyridazin-3-yl)-3-methyl-5-(trifluoromethyl)phenol
• IUPAC Name: 2-[6-[[(3R)-1-ethylpiperidin-3-yl]amino]pyridazin-3-yl]-3-methyl-5-(trifluoromethyl)phenol
• SMILES: CC1=CC(C(F)(F)F)=CC(O)=C1C2=NN=C(N[C@@H]3CCCN(CC)C3)C=C2
• InChI: InChI=1S/C19H23F3N4O/c1-3-26-8-4-5-14(11-26)23-17-7-6-15(24-25-17)18-12(2)9-13(10-16(18)27)19(20,21)22/h6-7,9-10,14,27H,3-5,8,11H2,1-2H3,(H,23,25)/t14-/m1/s1
• InChI Key: UVVZGYXCKGWWCC-CQSZACIVSA-N
• Appearance: Off-white to light brown solid
• Shipping: Room temperature; may vary elsewhere.
• Storage Conditions: 4 °C, protect from light