Structure

(R)-CDK2 degrader 6

CAS
3083777-50-5
Catalog Number
ACM-MG-3083777505
Category
Molecular Glues
Molecular Weight
511.44
Molecular Formula
C23H22F5N5O3

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Specification

Description
(R)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 27.0 nM in 24 h. (R)-CDK2 degrader 6 can be used for breast cancer research.
SMILES
FC(F)(C12CC(C2)(C3=NN=C(N[C@@H]4[C@H](N(C5=CC(F)=C([C@@H]6C(NC(CC6)=O)=O)C(F)=C5)C4)C)O3)C1)F
Appearance
Solid
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
-20 °C, stored under nitrogen, away from moisture

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