Ascomycin

• CAS: 11011-38-4
• Catalog Number: ACM-MG-11011384
• Category: Molecular Glues
• Molecular Weight: 729.03
• Molecular Formula: C43H69NO12
• Description: FKBP ligand; immunosuppressant
• Synonyms: FK-520; FR-900520; Fermentation product from Streptomyces hygroscopicus
• IUPAC Name: 17-ethyl-1,14-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
• SMILES: CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C
• InChI: InChI=1S/C43H69NO12/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)44-16-12-11-13-31(44)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-32(45)35(22-29)52-7/h18,20,25,27-33,35-39,45-46,51H,10-17,19,21-23H2,1-9H3
• InChI Key: ZDQSOHOQTUFQEM-UHFFFAOYSA-N
• Solubility: Soluble in DMSO (up to 50 mg/ml), or in ethanol (up to 50 mg/ml with warming)
• Appearance: White solid
• Shipping: Room temperature
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20 °C for up to 3 months.
• Storage Conditions: Store at -20 °C