CAS
1044797-96-7 Purity
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1044797-96-7 Purity
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AR Degrader-3
CAS
1182011-65-9
Catalog Number
ACM-MG-1182011659
Category
Molecular Glues
Molecular Weight
435.50
Molecular Formula
C23H21N3O4S
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- Product Description
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Specification
Description
AR Degrader-3 is an orally active molecular glue that targets AR/ARV7 and induces the degradation of AR and ARV7 through the ubiquitin-proteasome pathway (UPP).
Synonyms
EX-A16327
IUPAC Name
4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzamide
SMILES
CC1=NOC(C)=C1COC2=CC=C(C(NC3=NC(C4=CC=C(OC)C=C4)=CS3)=O)C=C2
InChI
InChI=1S/C23H21N3O4S/c1-14-20(15(2)30-26-14)12-29-19-10-6-17(7-11-19)22(27)25-23-24-21(13-31-23)16-4-8-18(28-3)9-5-16/h4-11,13H,12H2,1-3H3,(H,24,25,27)
InChI Key
QQDVQSAQUAHWDB-UHFFFAOYSA-N
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
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