(R)-CR8 trihydrochloride

• CAS: 1786438-30-9
• Catalog Number: ACM-MG-1786438309
• Category: Molecular Glues
• Molecular Weight: 540.92
• Molecular Formula: C24H32Cl3N7O
• Description: (R)-CR8 trihydrochloride acts as a molecular glue degrader that depletes cyclin K.
• Synonyms: CR8, (R)-Isomer trihydrochloride
• IUPAC Name: (2R)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol;trihydrochloride
• SMILES: CC[C@@H](NC1=NC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4N=CN(C(C)C)C4=N1)CO.[H]Cl.[H]Cl.[H]Cl
• InChI: InChI=1S/C24H29N7O.3ClH/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20;;;/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(H2,26,28,29,30);3*1H/t19-;;;/m1.../s1
• InChI Key: ORYSYXHQFOWNDK-RGFWRHHQSA-N
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: 4 °C, sealed storage, away from moisture