V1

• CAS: 1802770-18-8
• Catalog Number: ACM-MG-1802770188
• Category: Molecular Glues
• Molecular Weight: 524.62
• Molecular Formula: C31H32N4O4
• Description: V1 acts as a molecular glue to stabilize the symmetrical dimer of the TrkA kinase domains. V1 binds to the ATP-binding site and simultaneously engages in the dimeric interface of TrkA.
• Synonyms: VMD928
• IUPAC Name: 4-[[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxoanthracen-1-yl]amino]benzoic acid
• SMILES: NC1=C2C(=O)C3=C(C=CC=C3)C(=O)C2=C(NC2=CC=C(C=C2)C(O)=O)C=C1N1CCN(CC1)C1CCCCC1
• InChI: InChI=1S/C31H32N4O4/c32-28-25(35-16-14-34(15-17-35)21-6-2-1-3-7-21)18-24(33-20-12-10-19(11-13-20)31(38)39)26-27(28)30(37)23-9-5-4-8-22(23)29(26)36/h4-5,8-13,18,21,33H,1-3,6-7,14-17,32H2,(H,38,39)
• InChI Key: YLGUWQFLCMWHDK-UHFFFAOYSA-N
• Solubility: Soluble in DMSO, DMF
• Appearance: White solid
• Shipping: Room temperature
• Storage Conditions: Refrigerated