N-(4-Aminobenzoyl)-L-glutamic acid

• CAS: 4271-30-1
• Catalog Number: ACM4271301-1
• Category: Amino Acids
• Molecular Weight: 266.25
• Synonyms: N-(p-Aminobenzoyl)glutamic acid
• SMILES: Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1
• InChI Key: GADGMZDHLQLZRI-VIFPVBQESA-N
• Melting Point: 175 ℃(dec.)
• Application: N-(4-Aminobenzoyl)-L-glutamic acid (ABG) is used as a strong UV absorbing tag for the derivitization of oligosaccharides to enhance their detection in analytical methods such as capillary zone electrophoresis (CZE).
• Assay: ≥98% (TLC)
• Beilstein: 2816320
• Biochemical Physiological Action: N-p-Aminobenzoyl)-L-glutamic acid is a folate catabolite that can be metabolized by bacterial p-aminobenzoate auxotrophs possessing the enzyme p-aminobenzoyl-glutamate hydrolase.
• Color: off-white to beige
• EC Number: 224-261-7
• Form: powder
• MDL Number: MFCD00042821
• NACRES: NA.26
• PubChem ID: 24890463
• Quality Level: 200
• Storage Temperature: -20℃

Synthetic Use

Upstream Synthesis Route 1

• 6758-40-3

• 4271-30-1

Reference: [1] Patent: CN105439895, 2016, A, . Location in patent: Paragraph 0029; 0030

Upstream Synthesis Route 2

• 233600-78-7

• 4271-30-1

Reference: [1] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 10, p. 1311 - 1323

Upstream Synthesis Route 3

• 56-86-0

• 4271-30-1

Reference: [1] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 10, p. 1311 - 1323
[2] Journal of the Chemical Society, 1949, p. 1401,1404

Downstream Synthesis Route 1

• 64-18-6
• 4271-30-1

• 93528-16-6

Reference: [1]Patent: US2740784,1954,

Downstream Synthesis Route 2

• 1073-99-0
• 5221-17-0
• 4271-30-1

• 103207-69-8

Reference: [1]Patent: US2740784,1954,

Downstream Synthesis Route 3

• 3240-72-0
• 5221-17-0
• 4271-30-1

• 25663-25-6

Reference: [1]Patent: US2478873,1947,

* For details of the synthesis route, please refer to the original source to ensure accuracy.