Structure

MRT-31619

Catalog Number
ACM-MG-00078
Category
Molecular Glues
Molecular Weight
486.56
Molecular Formula
C28H30N4O4

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Specification

Description
MRT-31619 is a molecular gel degrader (MGD) targeting CRBN. MRT-31619 drives the self-dimerization of the E3 ligase by mimicking the degradation subunit, and promotes its rapid, effective and selective degradation through the ubiquitin-proteasome system.
SMILES
O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=C(C=C3)N4CCC5(C4)CCN(CC5)C(C6=CC=CC=C6)=O
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.

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