GR-14-3-3 stabilizer-1

• CAS: 271798-59-5
• Catalog Number: ACM-MG-271798595
• Category: Molecular Glues
• Molecular Weight: 317.79
• Molecular Formula: C15H12ClN3OS
• Description: GR-14-3-3 stabilizer-1 (compound 10) is a molecular glue stabilizer that can be used to prepare molecular glues targeting glucocorticoids (GR) and block the interaction between GR and 14-3-3.
• IUPAC Name: 3-[(4-chlorophenyl)sulfanylmethyl]-4-phenyl-1H-1,2,4-triazol-5-one
• SMILES: O=C1NN=C(CSC2=CC=C(C=C2)Cl)N1C3=CC=CC=C3
• InChI: InChI=1S/C15H12ClN3OS/c16-11-6-8-13(9-7-11)21-10-14-17-18-15(20)19(14)12-4-2-1-3-5-12/h1-9H,10H2,(H,18,20)
• InChI Key: XZAALUVKVHHSCU-UHFFFAOYSA-N
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at -20 °C