Structure

HQ005

CAS
2750644-31-4
Catalog Number
ACM-MG-2750644314
Category
Molecular Glues
Molecular Weight
361.44
Molecular Formula
C15H15N5O2S2

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Specification

Description
HQ005 is a Molecular glue degrader of cyclin K (DC50 = 41 nM).
Synonyms
2-(2-{[6-(hydroxymethyl)pyridin-2-yl]amino}-1,3-thiazol-4-yl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide
IUPAC Name
2-[2-[[6-(hydroxymethyl)pyridin-2-yl]amino]-1,3-thiazol-4-yl]-N-(5-methyl-1,3-thiazol-2-yl)acetamide
SMILES
CC1=CN=C(NC(=O)CC2=CSC(NC3=NC(CO)=CC=C3)=N2)S1
InChI
InChI=1S/C15H15N5O2S2/c1-9-6-16-14(24-9)20-13(22)5-11-8-23-15(18-11)19-12-4-2-3-10(7-21)17-12/h2-4,6,8,21H,5,7H2,1H3,(H,16,20,22)(H,17,18,19)
InChI Key
RCCDIUZAPKBQLV-UHFFFAOYSA-N
Solubility
Soluble in DMSO, DMF
Appearance
White solid
Shipping
Room temperature
Storage Conditions
Refrigerated

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