CAS
2654011-51-3 Purity
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2654011-51-3 Purity
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DEG-35
CAS
2734910-37-1
Catalog Number
ACM-MG-2734910371
Category
Molecular Glues
Molecular Weight
443.45
Molecular Formula
C25H21N3O5
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Specification
Description
DEG-35 is a CRBN-dependent, dual IKZF2 and CK1α molecule glue degrader, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. DEG-35 activates the p53 apoptosis pathway. DEG-35 can be used in the research for Acute Myeloid Leukemia (AML).
SMILES
COC1=CC2=C(C=C(C=C2)C(NC3=CC4=C(C(N(C4)C5CCC(NC5=O)=O)=O)C=C3)=O)C=C1
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.
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