BTX-7312

• Catalog Number: ACM-MG-00007
• Category: Molecular Glues
• Molecular Weight: 926.40
• Molecular Formula: C45H52ClF4N9O6
• Description: BTX-7312 is a cereblon-based SOS1 bifunctional degrader and a molecular glue. BTX-7312 reduces downstream signaling markers pERK and pS6 and shows antiproliferative activity in various KRAS-mutated cells.
• SMILES: FC(F)(F)C1=CC([C@@H](C)NC2=NC(Cl)=NC3=C2CN(C(C4(OC)CCN(C(CCCCN5CCC(C6=CC(CN(C7CCC(NC7=O)=O)C8=O)=C8C=C6F)CC5)=O)CC4)=O)C3)=CC(N)=C1
• Appearance: White to off-white solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at -20 °C