BRD4 degrader-1

• Catalog Number: ACM-MG-00006
• Category: Molecular Glues
• Molecular Weight: 559.10
• Molecular Formula: C25H27ClN6O3S2
• Description: BRD4 degrader-1 (Compound ML 1-50) is a monovalent and covalent molecular glue BRD4 degrader. BRD4 degrader-1 targets DCAF16 (E3 ligase) and degrades both the long and short isoforms of BRD4 in cells.
• SMILES: O=C(N1CCN(S(=O)(C=C)=O)CC1)C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.