Structure

(1S,2S,3R)-PLX-4545

CAS
2892066-42-9
Catalog Number
ACM-MG-2892066429
Category
Molecular Glues
Molecular Weight
473.56
Molecular Formula
C28H31N3O4

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Specification

Description
(1S,2S,3R)-PLX-4545 is the (1S,2S,3R) enantiomer of PLX-4545. PLX-4545 is an orally active and selective cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios).
SMILES
O=C([C@H](N(CC1=C2C=CC(O[C@@H]3[C@@H](N4CC(C5=CC=CC=C5)C4)CCCC3)=C1)C2=O)CC6)NC6=O
Appearance
Solid
Shipping
Room temperature; may vary elsewhere.
Storage Conditions
Store at -20 °C

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