α-Copaene

CAS
3856-25-5
Catalog Number
ACM3856255
Category
Main Products
Molecular Weight
204.4
Molecular Formula
C15H24

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Liquid

α-Copaene as a Natural Antimicrobial Agent for Food Preservation

Antimicrobial activity and mechanism of α-copaene against foodborne pathogenic bacteria and its application in beef soup Chen S, et al. LWT, 2024, 195, 115848.

α-Copaene exhibits potent antibacterial activity against major foodborne pathogens, including Staphylococcus aureus, Escherichia coli, Bacillus cereus, and Shigella bogdii. With a minimum inhibitory concentration (MIC) of 0.5-1 μL/mL and a minimum bactericidal concentration (MBC) of 2-4 μL/mL, α-copaene effectively disrupts bacterial cell membranes, leading to increased permeability and structural damage, as confirmed by scanning electron microscopy and flow cytometry. Moreover, α-copaene inhibits biofilm formation by reducing bacterial cell surface hydrophobicity, further preventing microbial adhesion and persistence. Hemolytic and cytotoxicity assessments indicate its biosafety, supporting its potential as a food-grade preservative. In practical application, α-copaene at 4 μL/mL effectively inhibited bacterial growth in beef soup, demonstrating its efficacy in real food matrices.

What is the molecular formula of (-)-Alpha-copaene?

The molecular formula of (-)-Alpha-copaene is C15H24.

What is the molecular weight of (-)-Alpha-copaene?

The molecular weight of (-)-Alpha-copaene is 204.35 g/mol.

What are some synonyms for (-)-Alpha-copaene?

Some synonyms for (-)-Alpha-copaene are Copaene, (-)-alpha-Copaene, and 3856-25-5.

What is the IUPAC name of (-)-Alpha-copaene?

The IUPAC name of (-)-Alpha-copaene is (1R,2S,6S,7S,8S)-1,3-dimethyl-8-propan-2-yltricyclo[4.4.0.0 2,7 ]dec-3-ene.

What is the InChIKey of (-)-Alpha-copaene?

The InChIKey of (-)-Alpha-copaene is VLXDPFLIRFYIME-BTFPBAQTSA-N.

What is the canonical SMILES of (-)-Alpha-copaene?

The canonical SMILES of (-)-Alpha-copaene is CC1=CCC2C3C1C2(CCC3C(C)C)C.

How many hydrogen bond donor counts does (-)-Alpha-copaene have?

(-)-Alpha-copaene has 0 hydrogen bond donor counts.

What is the xLogP3-AA value of (-)-Alpha-copaene?

The xLogP3-AA value of (-)-Alpha-copaene is 4.5.

What is the topological polar surface area of (-)-Alpha-copaene?

The topological polar surface area of (-)-Alpha-copaene is 0?2.

How many defined atom stereocenter count does (-)-Alpha-copaene have?

(-)-Alpha-copaene has 5 defined atom stereocenter counts.

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