Tricaprin

• Catalog Number: ACM621716
• Product Name: Tricaprin
• CAS: 621-71-6
• Category: Glycerides
• Synonyms: Glyceryltricaprate
• IUPAC Name: 2,3-Di(decanoyloxy)propyl decanoate
• Molecular Weight: 554.84
• Molecular Formula: C33H62O6
• Canonical SMILES: CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC
• InChI: InChI=1S/C33H62O6/c1-4-7-10-13-16-19-22-25-31(34)37-28-30(39-33(36)27-24-21-18-15-12-9-6-3)29-38-32(35)26-23-20-17-14-11-8-5-2/h30H,4-29H2,1-3H3
• InChI Key: LADGBHLMCUINGV-UHFFFAOYSA-N
• Boiling Point: 254 °C/5 mmHg
• Melting Point: 31-32 °C
• Flash Point: 20 °C
• Density: 0.98 g/ml at 20 °C
• Solubility: water, 1.334e-008 mg/L @ 25 °C (est)
• Appearance: Solid
• Storage: -20 °C
• Assay: 0.97
• CNo.Chain: C10:0
• Complexity: 543
• EC Number: 210-702-0
• Exact Mass: 554.45463969
• Glyceride: Tridecanoin (Caprin)
• MDL Number: MFCD00036239
• Monoisotopic Mass: 554.45463969
• Packaging: 1 kg
• Physical State: Colorless liquid
• Refractive Index: 1.44
• Storage Conditions: -20°C
• Topological Polar Surface Area: 78.9 Ų

Case Study

The Potential of Tricaprin in Preventing the Development Of AAA

Kugo, Hirona, et al. Biomedicine & Pharmacotherapy, 2023, 160, 114299.

Medium-chain triglycerides (MCT) are composed of medium-chain fatty acids (MCFA) with a backbone of 8-10 carbon atoms. MCTs are used clinically to treat metabolic and neurological diseases, and their safety has been demonstrated. Recently, studies have used aortic hypoperfusion-induced abdominal aortic aneurysm (AAA) models to identify AAA drug candidates.
Effects of MCT on AAA
· Tricaprin can be effective to prevent or treat abdominal aortic aneurysm.
· Tricaprin can suppress smooth muscle cells dysfunction in the aortic wall.
· Tricaprin can have potent pre-clinical activities, but not tricaprylin.
· Tricaprin can be a promising candidate to reduce the risk of AAA rupture.