Thalidomide-NH-CBP/p300 ligand 2

• CAS: 2484739-21-9
• Catalog Number: ACM-MG-2484739219
• Category: Molecular Glues
• Molecular Weight: 922.03
• Molecular Formula: C48H57F2N11O6
• Description: Thalidomide-NH-CBP/p300 ligand 2 is a PROTAC-based CBP and p300 degrader.
• IUPAC Name: 3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[1-[8-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]octanoyl]piperidin-4-yl]-N-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
• SMILES: O=C(N1CC2=C(CC1)N(C3CCN(CC3)C(CCCCCCCNC4=CC=C5C(N(C6C(NC(CC6)=O)=O)C(C5=C4)=O)=O)=O)N=C2N7C8=C(CCC7)C=C(C9=CN(C)N=C9)C(C(F)F)=C8)NC
• InChI: InChI=1S/C48H57F2N11O6/c1-51-48(67)58-22-17-38-37(28-58)44(59-19-8-9-29-23-34(30-26-53-56(2)27-30)35(43(49)50)25-40(29)59)55-61(38)32-15-20-57(21-16-32)42(63)10-6-4-3-5-7-18-52-31-11-12-33-36(24-31)47(66)60(46(33)65)39-13-14-41(62)54-45(39)64/h11-12,23-27,32,39,43,52H,3-10,13-22,28H2,1-2H3,(H,51,67)(H,54,62,64)
• InChI Key: ZTXHWKWVLNMDFC-UHFFFAOYSA-N
• Appearance: Light yellow to green yellow solid
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: -20 °C, sealed storage, away from moisture and light