(Rac)-Cemsidomide

• CAS: 2504233-68-3
• Catalog Number: ACM-MG-2504233683
• Category: Molecular Glues
• Molecular Weight: 469.53
• Molecular Formula: C28H27N3O4
• Description: (Rac)-Cemsidomide ((Rac)-CFT7455) is the racemate of Cemsidomide with antitumor activity. Cemsidomide is a ubiquitin ligase pathway Ikaros/Aiolos degrader with molecular glue activity. Cemsidomide has a GI50 of 0.05 nM for NCIH929.1 cells.
• Synonyms: (Rac)-CFT7455
• IUPAC Name: 3-[6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-2-oxobenzo[cd]indol-1-yl]piperidine-2,6-dione
• SMILES: O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C(C4=CC=CC1=C43)CC5=CC=C(C=C5)CN6CCOCC6
• InChI: InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33)
• InChI Key: MUKCJOOKCZSQNW-UHFFFAOYSA-N
• Appearance: Light yellow to yellow soild
• Shipping: Generally, shipped at room temperature in continental US; may vary elsewhere.
• Storage Conditions: Store at -20 °C