Li C1, Wang F2, Douglas G3, Zhang Z4, Guidoin R4, Wang L2.
J Mech Behav Biomed Mater. 2016 Dec 15;69:39-49. doi: 10.1016/j.jmbbm.2016.11.005. [Epub ahead of print]Vascular grafts made by tissue engineering processes are prone to buckling and twisting, which can impede blood flow and lead to collapse of the vessel. These vascular conduits may suffer not only from insufficient tensile strength, but also from vulnerabilities related to compression, torsion, and pulsatile pressurization. Aiming to develop a tissue engineering-inspired blood conduit, composite vascular graft (cVG) prototypes were created by combining a flexible polylactic acid (PLA) knitted fabric with a soft polycaprolactone (PCL) matrix. Read More