Nocodazole

• Catalog Number: ACM31430189
• Product Name: Nocodazole
• CAS: 31430-18-9
• Category: Inhibitors
• Description: Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl, and activates CRISPR/Cas9.
• Synonyms: [5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL]CARBONIC ACID, METHYL ESTER;METHYL[5-(2-THIENYLCARBONYL)-1H-BENZIMADAZOL-2-YL]CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMIDAZOL-2-YL)CARBAMATE;METHYL [5-(2-THIENYLCARBONYL)-1H-BENZ-IMIDAZOLE-2-YL]-CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMODAZOL-2YL)-CARBAMATE;METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE;NOCODAZOLE;R 17934
• Molecular Weight: 301.32
• Molecular Formula: C₁₄H₁₁N₃O₃S
• Melting Point: 300°C (dec.)
• Density: 1.490
• Appearance: powder
• Hazard Statements: T,C,F,Xn
• Safety Description: 53-45-36/37/39-26-16-36/37
• Supplemental Hazard Statements: H341-H361d
• Symbol: GHS08

Custom Q&A

What is the molecular formula of Nocodazole?

The molecular formula of Nocodazole is C14H11N3O3S.

What is the molecular weight of Nocodazole?

The molecular weight of Nocodazole is 301.32 g/mol.

How is Nocodazole described in terms of its physical appearance?

Nocodazole is described as a white powder.

What is the role of Nocodazole as stated in the reference?

Nocodazole has a role as an antineoplastic agent, a tubulin modulator, an antimitotic, and a microtubule-destabilizing agent.

How does Nocodazole exert its effect?

Nocodazole exerts its effect by depolymerizing microtubules.

What are some synonyms for Nocodazole?

Some synonyms for Nocodazole include Oncodazole, R 17934, and Nocodazolum.

What is the IUPAC name of Nocodazole?

The IUPAC name of Nocodazole is methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate.

What is the InChIKey of Nocodazole?

The InChIKey of Nocodazole is KYRVNWMVYQXFEU-UHFFFAOYSA-N.

What is the CAS number of Nocodazole?

The CAS number of Nocodazole is 31430-18-9.

What are some other identifiers for Nocodazole?

Other identifiers for Nocodazole include European Community (EC) Number, UNII, UN Number, ChEMBL ID, KEGG ID, NCI Thesaurus Code, and more.