Description
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
Synonyms
inf1837;Lanceat;Meralen;N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid;N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilate;n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilicaci;n-(m-trifluoromethylphenyl)-2-aminobenzoicacid;Nichisedan