Flufenamic acid

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Catalog Number
ACM530789
Product Name
Flufenamic acid
Structure
Structure
CAS
530-78-9
Category
Inhibitors
Description
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
Synonyms
inf1837;Lanceat;Meralen;N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid;N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilate;n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilicaci;n-(m-trifluoromethylphenyl)-2-aminobenzoicacid;Nichisedan
Molecular Weight
281.23
Molecular Formula
C14H10F3NO2
Melting Point
132-135°C(lit.)
Hazard Statements
Xn
Safety Description
26
Supplemental Hazard Statements
H302-H335-H301-H315-H319
Symbol
GHS07,GHS06
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