Dimethyl malonate

• Catalog Number: ACM108598
• Product Name: Dimethyl malonate
• CAS: 108-59-8
• Category: Inhibitors
• Description: Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.
• Synonyms: 2,2-Dimethylpropanedioate
• IUPAC Name: Dimethyl propanedioate
• Molecular Weight: 132.11
• Molecular Formula: C5H8O4
• Canonical SMILES: O=C(OC)CC(OC)=O
• InChI: InChI=1S/C5H8O4/c1-8-4(6)3-5(7)9-2/h3H2,1-2H3
• InChI Key: BEPAFCGSDWSTEL-UHFFFAOYSA-N
• Boiling Point: 180-181 °C
• Melting Point: -62 °C
• Flash Point: 194 °F
• Density: 1.156 g/mL at 25 °C(lit.)
• Solubility: water, 9.951e+004 mg/L @ 25 °C (est)
• Appearance: Colorless clear oily liquid (est)
• Storage: Pure form-20°C,3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Assay: 0.9999
• EC Number: 203-597-8
• Exact Mass: 132.04225873
• Hazard Statements: Xi
• MDL Number: MFCD00008460
• Monoisotopic Mass: 132.04225873
• Packaging: 1 kg
• Physical State: Liquid
• Refractive Index: n20/D 1.413(lit.)
• Safety Description: 26-36
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsMeliaceaeMelia azedarach L.
• Stability: Stable. Incompatible with strong oxidizing agents. Flammable.
• Storage Conditions: Below +30 °C
• Supplemental Hazard Statements: H315-H319-H335-H227
• Symbol: GHS07
• Topological Polar Surface Area: 52.6 Ų