Brefeldin a

• Catalog Number: ACM20350156
• Product Name: Brefeldin a
• CAS: 20350-15-6
• Category: Inhibitors
• Description: Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity.
• Synonyms: NECTROLIDE;SYNERGISIDIN;4h-cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-de;cahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-;cyanaein;CYANEIN;DECUMBIN;GAMMA-4-DIHDYROXY-2-(6-HYDROXY-1-HEPTENYL)-4-CYCLOPENTANECROTONIC ACID LAMBDA-LACTONE
• Molecular Weight: 280.36
• Molecular Formula: C₁₆H₂₄O₄
• Melting Point: 200-205°C
• Flash Point: 87°C
• Hazard Statements: Xn,T
• Safety Description: 24/25-45-36-26
• Supplemental Hazard Statements: H301-H302
• Symbol: GHS07,GHS06