Berberine

• Catalog Number: ACM2086831
• Product Name: Berberine
• CAS: 2086-83-1
• Category: Inhibitors
• Description: Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties.
• Synonyms: Berbericine
• IUPAC Name: 16,17-Dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene
• Molecular Weight: 336.37
• Molecular Formula: C20H18NO4
• Canonical SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC
• InChI: InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1
• InChI Key: YBHILYKTIRIUTE-UHFFFAOYSA-N
• Boiling Point: 486.8 °C
• Melting Point: 204-206 °C
• Density: 1.2976 g/cm³
• Appearance: White to yellow crystals
• Storage: Inert atmosphere, room temperature
• Complexity: 488
• Exact Mass: 336.12358306
• LogP: -0.99
• Monoisotopic Mass: 336.12358306
• pKa: 2.47(at 25 °C)
• PSA: 40.80000
• Refractive Index: 1.5800
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsRanunculaceaeCoptis chinensis Franch.
• Topological Polar Surface Area: 40.8 Ų