Polyglycolic acid

• CAS: 26009-03-0
• Catalog Number: ALC-FP-26009030
• Category: Featured Products
• Molecular Weight: Mw 10000-20000
• Melting Point: 220-240 ºC
• Appearance: Yellow to light brown solid
• Heavy Metal: ≤10 ppm(as Pb)
• Ignition Loss: ≤ 0.5%
• Melt Flow Rate: 10-20 g/10min
• Monomer Residue: ≤ 1%
• pH: >6.5
• Sample Lot No.: A24C809EW
• Sn Residue: ≤ 200 ppm
• Water Content: ≤ 0.5%

Case Study

Polyglycolic Acid (PGA) for Seawater-Degradable Antibacterial Composite Applications

Tang X, et al. International Journal of Biological Macromolecules, 2025, 318(2), 144993.

Seawater-degradable polyglycolic acid (PGA) antibacterial composites were fabricated via melt-blending with chitosan (CS), a multifunctional epoxy chain extender (ADR), and an organic phosphite antioxidant (AO) to enhance mechanical and thermal properties while maintaining biodegradability. PGA was pre-dried at 40 °C under vacuum for 24 h, then premixed with CS, ADR, and AO before compounding in a torque rheometer at 230 °C, 50 Hz rotor speed, for 10 min. ADR and AO mitigated PGA's degradation induced by CS through ring-opening chain extension and free-radical scavenging, resulting in a 45.9 % reduction in melt flow rate and a 19.2 % increase in elongation at break. Uniform CS dispersion enabled strong antibacterial efficacy against E. coli and S. aureus (>99.87 %) via amino cation-mediated membrane disruption, demonstrating the composite's practical potential in high-end biomedical and environmental applications.

Polyglycolic Acid for Enhanced Barrier and Mechanical Properties in PET Blends

Tiwari R, et al. Polymer, 2025, 335, 128761.

This study investigates the experimental application of polyglycolic acid (PGA) in polyethylene terephthalate (PET) blend films to improve barrier, thermal, and mechanical properties. PET/PGA blends were prepared via melt-blending using a micro-compounder, with 1 phr Joncryl ADR employed as a compatibilizer to enhance interfacial adhesion and miscibility. Scanning electron microscopy confirmed improved interface quality in PET/PGA blends. Barrier performance testing revealed a 62% enhancement in oxygen permeability and a 41% improvement in water vapor resistance for PET/20% PGA compared to neat PET. Mechanical evaluation demonstrated a 42% increase in tensile strength and a 22.4% increase in modulus, surpassing PET/LCP blends. The experimental results highlight PGA's effective role in producing all-polyester films with superior barrier and mechanical performance while maintaining recyclability.

Polyglycolic Acid Nanofibrous Membranes for High-Efficiency Antibacterial Air Filtration

Yin N, et al. European Polymer Journal, 2023, 200, 112498.

In this study, biodegradable polyglycolic acid (PGA) nanofibrous membranes loaded with antibacterial ε-polylysine-dialdehyde microcrystalline celluloses (PGA@EPL-DAMCs) were fabricated via electrospinning. PGA solutions (6 % in HFIP) were stirred at 75 °C for 6 h to ensure homogeneity. EPL-DAMCs were incorporated at varying ratios (3-9 % w/w) to evaluate their impact on fiber morphology and antibacterial activity. Solutions were sonicated for 90 min to obtain uniform suspensions prior to electrospinning. Additional trials investigated the effect of different lysine contents (14-54 %) in DAMCs on fiber properties. The resulting PGA@EPL-DAMC-24 % membrane achieved superior filtration efficiency (99.83 %) and antibacterial rates against E. coli and S. aureus (>99.9 %). Membrane degradation studies confirmed its potential as a biodegradable, environmentally friendly material for medical protective applications with highly efficient air filtration and antimicrobial performance.