CAS
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MYC degrader 1 TFA
Catalog Number
ACM-MG-00037
Category
Molecular Glues
Molecular Weight
740.09
Molecular Formula
C34H32ClF6N5O5
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Specification
Description
MYC degrader 1 TFA (compound A80.2HCl) is an orally available MYC molecular glues degrader with anti-tumor activity. MYC degrader 1 TFA restores pRB1 protein activity and re-establishes sensitivity of MYC overexpressing cancer cells to CDK4/6 inhibitors.
SMILES
ClC1=CC(C2=CC(C(F)(F)F)=C(N3CCC(CNCC4=CC(CN(C5C(NC(CC5)=O)=O)C6=O)=C6C=C4)CC3)N=C2)=CC=C1.O=C(O)C(F)(F)F
Appearance
White to off-white solid
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
-20 °C, sealed storage, away from moisture and light
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