Structure

mrt-5702D

Catalog Number
ACM-MG-00036
Category
Molecular Glues
Molecular Weight
621.11
Molecular Formula
C30H29ClN6O5S

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Specification

Description
mrt-5702D is a molecular glue degrader targeting cereblon (CRBN). mrt-5702D forms a CRBN-MRT-5702D-G3BP2 ternary complex to activate the ubiquitin-proteasome system for G3BP2 degradation. mrt-5702D is promising for research of G3BP2-related cancers (e.g., breast cancer, lung cancer) and neurodegenerative diseases.
SMILES
C[C@H]1C2=CC=CC=C2C[C@H](N1S(=O)(CC3=CC=CC=C3Cl)=O)C(NCC4=CC5=NC=C(N5C=C4)N6CCC(NC6=O)=O)=O
Shipping
Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions
Please store the product under the recommended conditions.

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Alfa Chemistry

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