Fmoc-Thr(ß-D-GlcNAc(Ac)3)-OH

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  • 160168-40-1
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Catalog Number
ACM160168401
Product Name
Fmoc-Thr(ß-D-GlcNAc(Ac)3)-OH
Structure
Structure
CAS
160168-40-1
Category
Amino Acids
Description
Fmoc-Thr(GlcNAc)3(Ac) is a complex molecule that belongs to the family of Fmoc-protected amino acids. It is typically used in the synthesis of peptides and serves as an important building block. The molecule has a beta configuration of GlcNAc(Ac)3, which refers to three N-acetylated glucosamine residues, and an acetyl group attached to the beta carboxyl group of the threonine residue. Since their introduction in the 1980s, Fmoc-protected amino acids have become important in the field of peptide synthesis, and Fmoc-Thr(GlcNAc)3(Ac) is no exception.
Synonyms
Fmoc-Thr(GlcNAc)3(Ac)
IUPAC Name
(2S,3R)-3-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid
Molecular Weight
670.7
Molecular Formula
C33H38N2O13
Canonical SMILES
CC(C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC4C(C(C(C(O4)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C
InChI
1S/C33H38N2O13/c1-16(27(31(40)41)35-33(42)44-14-25-23-12-8-6-10-21(23)22-11-7-9-13-24(22)25)45-32-28(34-17(2)36)30(47-20(5)39)29(46-19(4)38)26(48-32)15-43-18(3)37/h6-13,16,25-30,32H,14-15H2,1-5H3,(H,34,36)(H,35,42)(H,40,41)/t16-,26-,27+,28-,29-,30-,32-/m1/s1
Boiling Point
857.1±65.0℃
Density
1.38±0.1g g/mL at 20 ℃(lit.)
Application
Fmoc-Thr(GlcNAc)3(Ac) has several applications in scientific experiments. It is a useful building block in the synthesis of peptide therapeutics. It can also be used in the synthesis of glycopeptides, which are peptides with one or more sugar units attached.
Exact Mass
670.237
Functional Group
Fmoc
LogP
3.0842
PSA
209.07
Storage Temperature
Store at -20℃
Type
Unusual Amino Acids, Glycosylated
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