Fmoc-Lys(Ac)-OH

• CAS: 159766-56-0
• Catalog Number: ACM159766560-1
• Category: Amino Acids
• Molecular Weight: 410.46
• Molecular Formula: C23H26N2O5
• Description: Building block for introduction of N-ε-acetyl-lysine amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-Lys(Ac)-OH, N-α-Fmoc-N-ε-acetyl-L-lysine
• InChI: 1S/C23H26N2O5/c1-15(26)24-13-7-6-12-21(22(27)28)25-23(29)30-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h2-5,8-11,20-21H,6-7,12-14H2,1H3,(H,24,26)(H,25,29)(H,27,28)/t21-/m0/s1
• InChI Key: HQLBYVWJOXITAM-NRFANRHFSA-N
• Application: Peptide synthesis.
• Assay: ≥97.0% (HPLC); ≥97.0% (acidimetric); ≥98% (TLC)
• Form: powder
• Functional Group: amine
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unusual Amino Acids, Acetylated

Synthetic Use

Upstream Synthesis Route 1

• 108-24-7

• 159766-56-0

Reference: [1] Angewandte Chemie - International Edition, 2011, vol. 50, # 47, p. 11167 - 11171

Upstream Synthesis Route 2

• 108-24-7

• 159766-56-0

Reference: [1] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 15, p. 5616 - 5625

Upstream Synthesis Route 3

• 108-24-7

• 159766-56-0

Reference: [1] Tetrahedron Letters, 2003, vol. 44, # 25, p. 4757 - 4759

Downstream Synthesis Route 1

• 29022-11-5
• 35661-39-3
• 71989-31-6
• 71989-26-9
• 146982-27-6
• 159766-56-0
• 471-25-0

• 1186083-96-4

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,p. 3775 - 3778

* For details of the synthesis route, please refer to the original source to ensure accuracy.