CAS
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Fmoc-Asp(OEpe)-OH
Catalog Number
ACMA00051080
Category
Amino Acids
Molecular Weight
453.53
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Specification
Description
An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group. The combination of Asp(OEpe) and the use of 1 M Oxyma Pure in DMF for Fmoc removal results in minimal aspartimde formation.
Synonyms
Fmoc-Asp(OEpe)-OH, N-α-Fmoc-(O-3-ethyl-pent-3-yl)aspartic acid
Application
Peptide synthesis.
Form
powder
Functional Group
carboxylic acid
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃
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